BCL3 anticorps (AA 118-307) (HRP)

N° du produit ABIN7971885

Cet anticorps Lapin Polyclonal détecte spécifiquement BCL3 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL3 anticorps (AA 118-307) (HRP) (ABIN7971885)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BCL3 anticorps (HRP)

Épitope: AA 118-307

Fonction: Anti-BCL3 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human BCL3 recombinant protein (Position: E118-Y307).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3

Sujet:

Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

Gene Full Name: BCL3 transcription coactivator

ID gène: 602

UniProt: P20749

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus