BCL3 anticorps (AA 118-420) (Fluoro594)

N° du produit ABIN7971894

Cet anticorps Lapin Polyclonal détecte spécifiquement BCL3 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL3 anticorps (AA 118-420) (Fluoro594) (ABIN7971894)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-BCL3 anticorps (Fluoro594)

Épitope: AA 118-420

Fonction: Anti-BCL3 Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PELI2 shares 97.4% amino acid (aa) sequence identity with mouse?PELI2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PELI2 recombinant protein (Position: D118-D420). Human PELI2 shares 97.4% amino acid (aa) sequence identity with mouse?PELI2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3

Sujet:

Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

Gene Full Name: BCL3 transcription coactivator

ID gène: 602

UniProt: P20749

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus