Survivin anticorps (AA 1-140) (Fluoro488)

N° du produit ABIN7972013

Cet anticorps anti-Survivin Polyclonal Lapin conjugué à Fluoro488 (ABIN7972013) détecte spécifiquement Survivin dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Survivin anticorps (AA 1-140) (Fluoro488) (ABIN7972013)

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Survivin est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-Survivin anticorps (Fluoro488)

Épitope: AA 1-140

Fonction: Anti-Survivin/BIRC5 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse Survivin shares 85%,91% amino acid (aa) sequence identity with human,rat Survivin,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Survivin recombinant protein (Position: M1-A140). Mouse Survivin shares 85% and 91% amino acid (aa) sequence identity with human and rat Survivin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: BIRC5

Sujet:

Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Gene Full Name: baculoviral IAP repeat-containing 5

Sequence Similarities: Belongs to the IAP family.

ID gène: 11799

UniProt: O70201

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding