Survivin anticorps (AA 1-140)

N° du produit ABIN7972021

L’anticorps anti-Survivin Polyclonal Lapin est utilisé pour la détection de Survivin dans des échantillons de Souris. Il a été validé pour WB, IHC et FACS.

Aperçu rapide pour Survivin anticorps (AA 1-140) (ABIN7972021)

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-Survivin anticorps

Épitope: AA 1-140

Fonction: Anti-Survivin/BIRC5 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse Survivin shares 85%,91% amino acid (aa) sequence identity with human,rat Survivin,respectively.

Attributs du produit: Anti-Survivin/BIRC5 Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Survivin recombinant protein (Position: M1-A140). Mouse Survivin shares 85% and 91% amino acid (aa) sequence identity with human and rat Survivin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mous Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: BIRC5

Sujet:

Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Gene Full Name: baculoviral IAP repeat-containing 5

Sequence Similarities: Belongs to the IAP family.

Poids moléculaire: 16 kDa

ID gène: 11799

UniProt: O70201

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding