BMPR1A anticorps (Middle Region) (Biotin)

N° du produit ABIN7972905

Cet anticorps Lapin Polyclonal détecte spécifiquement BMPR1A dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour BMPR1A anticorps (Middle Region) (Biotin) (ABIN7972905)

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR1A est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BMPR1A anticorps (Biotin)

Épitope: Middle Region

Fonction: Anti-BMPR1A Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human BMPR1A, which shares 95.8% amino acid (aa) sequence identity with mouse BMPR1A.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BMPR1A

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Autre désignation: BMPR1A

Sujet:

Background: The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Gene Full Name: bone morphogenetic protein receptor type 1A

ID gène: 657

UniProt: P36894

Pathways: Stem Cell Maintenance