CAMLG anticorps (Middle Region) (Fluoro550)

N° du produit ABIN7974119

Cet anticorps anti-CAMLG Polyclonal Lapin conjugué à Fluoro550 (ABIN7974119) détecte spécifiquement CAMLG dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CAMLG anticorps (Middle Region) (Fluoro550) (ABIN7974119)

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMLG est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-CAMLG anticorps (Fluoro550)

Épitope: Middle Region

Fonction: Anti-CAMLG Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CAMLG shares 91.7%,95.7% amino acid (aa) sequence identity with mouse,rat CAMLG,respectively.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CAMLG. Human CAMLG shares 91.7% and 95.7% amino acid (aa) sequence identity with mouse and rat CAMLG, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CAMLG

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Autre désignation: CAMLG

Sujet:

Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Gene Full Name: calcium modulating ligand

ID gène: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway