CREB3 anticorps (AA 1-352) (HRP)

N° du produit ABIN7974496

L’anticorps anti-CREB3 Polyclonal Lapin est utilisé pour la détection de CREB3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour CREB3 anticorps (AA 1-352) (HRP) (ABIN7974496)

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CREB3 anticorps (HRP)

Épitope: AA 1-352

Fonction: Anti-CREB3 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CREB3 recombinant protein (Position: M1-K352). Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CREB3

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Autre désignation: CREB3

Sujet:

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Gene Full Name: cAMP responsive element binding protein 3

ID gène: 10488

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response