CREB3 anticorps (AA 1-352) (APC)

N° du produit ABIN7974497

Cet anticorps anti-CREB3 Polyclonal Lapin conjugué à APC (ABIN7974497) détecte spécifiquement CREB3 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CREB3 anticorps (AA 1-352) (APC) (ABIN7974497)

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-CREB3 anticorps (APC)

Épitope: AA 1-352

Fonction: Anti-CREB3 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CREB3 recombinant protein (Position: M1-K352). Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CREB3

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Autre désignation: CREB3

Sujet:

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Gene Full Name: cAMP responsive element binding protein 3

ID gène: 10488

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response