CD2AP anticorps (AA 253-337)
Aperçu rapide pour CD2AP anticorps (AA 253-337) (ABIN7976470)
Antigène
Voir toutes CD2AP (Cd2ap) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- AA 253-337
-
Fonction
- Anti-CD2AP Antibody
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Attributs du produit
- Anti-CD2AP Antibody. Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells ELISA, 0.1-0.5 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
-
Autre désignation
- CD2AP
-
Sujet
-
Background: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein ly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Gene Full Name: CD2 associated protein
-
Poids moléculaire
- 80 kDa
-
ID gène
- 23607
-
UniProt
- Q9Y5K6
Antigène
-