CD3D anticorps (AA 22-171) (FITC)

N° du produit ABIN7976795

Cet anticorps anti-CD3D Polyclonal Lapin conjugué à FITC (ABIN7976795) détecte spécifiquement CD3D dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD3D anticorps (AA 22-171) (FITC) (ABIN7976795)

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3D est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-CD3D anticorps (FITC)

Épitope: AA 22-171

Fonction: Anti-CD3D Antibody FITC Conjugated

Homologie: Human CD3D shares 66%,70.7% amino acid (aa) sequence identity with mouse,rat CD3D,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD3D recombinant protein (Position: F22-K171). Human CD3D shares 66% and 70.7% amino acid (aa) sequence identity with mouse and rat CD3D, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD3D

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Autre désignation: CD3D

Sujet:

Background: T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene. The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Gene Full Name: CD3 delta subunit of T-cell receptor complex

ID gène: 915

UniProt: P04234

Pathways: TCR Signaling, CXCR4-mediated Signaling Events