CD3D anticorps (AA 22-171)

N° du produit ABIN7976800

L’anticorps anti-CD3D Polyclonal Lapin est utilisé pour la détection de CD3D dans des échantillons de Humain. Il a été validé pour WB, FACS et ELISA.

Aperçu rapide pour CD3D anticorps (AA 22-171) (ABIN7976800)

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3D est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-CD3D anticorps

Épitope: AA 22-171

Fonction: Anti-CD3D Antibody

Homologie: Human CD3D shares 66%,70.7% amino acid (aa) sequence identity with mouse,rat CD3D,respectively.

Attributs du produit: Anti-CD3D Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD3D recombinant protein (Position: F22-K171). Human CD3D shares 66% and 70.7% amino acid (aa) sequence identity with mouse and rat CD3D, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.2-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD3D

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Autre désignation: CD3D

Sujet:

Background: T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene. The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Gene Full Name: CD3 delta subunit of T-cell receptor complex

Poids moléculaire: 19 kDa

ID gène: 915

UniProt: P04234

Pathways: TCR Signaling, CXCR4-mediated Signaling Events