CD86 anticorps (AA 24-329) (Fluoro488)

N° du produit ABIN7977507

Cet anticorps Lapin Polyclonal détecte spécifiquement CD86 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CD86 anticorps (AA 24-329) (Fluoro488) (ABIN7977507)

Antigène: CD86

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD86 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-CD86 anticorps (Fluoro488)

Épitope: AA 24-329

Fonction: Anti-CD86 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CD86 shares 50% amino acid (aa) sequence identity with mouse CD86.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD86 recombinant protein (Position: A24-F329). Human CD86 shares 50% amino acid (aa) sequence identity with mouse CD86.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet:

Background: Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.

Gene Full Name: CD86 Molecule

Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

ID gène: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation