CXCR7 anticorps (C-Term) (Fluoro647)

N° du produit ABIN7979441

Cet anticorps anti-CXCR7 Polyclonal Lapin conjugué à Fluoro647 (ABIN7979441) détecte spécifiquement CXCR7 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CXCR7 anticorps (C-Term) (Fluoro647) (ABIN7979441)

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR7 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-CXCR7 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-GPCR RDC1/CXCR-7/ACKR3 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GPCR RDC1/CXCR-7/ACKR3, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CXCR7

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Autre désignation: ACKR3

Sujet:

Background: Atypical chemokine receptor 3 also known as C-X-C chemokine receptor type 7 (CXCR-7) and G-protein coupled receptor 159 (GPR159) is a protein that in humans is encoded by the ACKR3 gene. This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Gene Full Name: atypical chemokine receptor 3

ID gène: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling