Choline Acetyltransferase anticorps (AA 25-731) (APC)

N° du produit ABIN7979626

L’anticorps anti-Choline Acetyltransferase Polyclonal Lapin est utilisé pour la détection de Choline Acetyltransferase dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Choline Acetyltransferase anticorps (AA 25-731) (APC) (ABIN7979626)

Antigène: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Choline Acetyltransferase est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Choline Acetyltransferase anticorps (APC)

Épitope: AA 25-731

Fonction: Anti-Choline Acetyltransferase/CHAT Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Choline Acetyltransferase/CHAT recombinant protein (Position: T25-K731).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Choline Acetyltransferase

Antigène: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Autre désignation: CHAT

Sujet:

Background: Choline acetyltransferase  (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Gene Full Name: choline O-acetyltransferase

ID gène: 1103

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development