Choline Acetyltransferase anticorps (AA 131-704)
Aperçu rapide pour Choline Acetyltransferase anticorps (AA 131-704) (ABIN7979640)
Antigène
Voir toutes Choline Acetyltransferase (CHAT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 131-704
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Fonction
- Anti-Choline Acetyltransferase/CHAT Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Choline Acetyltransferase/CHAT Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Choline Acetyltransferase/CHAT recombinant protein (Position: L131-S704).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Autre désignation
- CHAT
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Sujet
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Background: Choline acetyltransferase(commonly abbreviated asChAT, but sometimesCAT) is atransferaseenzymeresponsible for the synthesis of theneurotransmitteracetylcholine. In humans, the choline acetyltransferase enzyme is encoded by theCHATgene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Gene Full Name: choline O-acetyltransferase
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Poids moléculaire
- 71 kDa
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ID gène
- 1103
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UniProt
- P28329
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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