Clusterin anticorps (AA 228-449) (Fluoro647)

N° du produit ABIN7980630

Cet anticorps Lapin Polyclonal détecte spécifiquement Clusterin dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Clusterin anticorps (AA 228-449) (Fluoro647) (ABIN7980630)

Antigène: Clusterin (CLU)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Clusterin est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Clusterin anticorps (Fluoro647)

Épitope: AA 228-449

Fonction: Anti-Apolipoprotein J/CLU Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human Apolipoprotein J recombinant protein (Position: S228-E449). Human Apolipoprotein J shares 76.1 %,75.2 % amino acid (aa) sequence identity with mouse,rat Apolipoprotein J,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Apolipoprotein J recombinant protein (Position: S228-E449). Human Apolipoprotein J shares 76.1 % and 75.2 % amino acid (aa) sequence identity with mouse and rat Apolipoprotein J, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: CLU

Sujet:

Background: Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene. This protein has several synonyms: dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI). Clusterin was mapped to mouse chromosome 14. Clusterin is a ubiquitously expressed molecule thought to influence a variety of processes including cell death. In the brain, it accumulates in dying neurons following seizures and hypoxic-ischemic (H-I) injury. clusterin may be a new therapeutic target to modulate non-caspase-dependent neuronal death following acute brain injury.

Gene Full Name: clusterin

Sequence Similarities: Belongs to the clusterin family.

ID gène: 1191

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling