C5 anticorps (AA 1-77)

N° du produit ABIN7981392

Cet anticorps Lapin Polyclonal détecte spécifiquement C5 dans WB et IHC. Il présente une réactivité avec des échantillons de Rat.

Aperçu rapide pour C5 anticorps (AA 1-77) (ABIN7981392)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-C5 anticorps

Épitope: AA 1-77

Fonction: Anti-C5/C5a Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Rat C5a shares 62%,82% amino acid (aa) sequences identity with human,mouse C5a,respectively.

Attributs du produit: Anti-C5/C5a Antibody. Tested in IHC, WB applications. This antibody reacts with Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat C5a recombinant protein (Position: D1-R77). Rat C5a shares 62% and 82% amino acid (aa) sequences identity with human and mouse C5a, respectively.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, RatWestern blot, 0.1-0.5 μg/mL, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: C5

Sujet:

Background: C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

Gene Full Name: complement component 5

Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family.

Poids moléculaire: 115 kDa

ID gène: 362119

UniProt: P08650

Pathways: Système du Complément, Carbohydrate Homeostasis