C5 anticorps (AA 19-294) (Fluoro647)

N° du produit ABIN7981402

L’anticorps anti-C5 Polyclonal Lapin est utilisé pour la détection de C5 dans des échantillons de Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour C5 anticorps (AA 19-294) (Fluoro647) (ABIN7981402)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-C5 anticorps (Fluoro647)

Épitope: AA 19-294

Fonction: Anti-C5 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse C5 recombinant protein (Position: Q19-D294).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: C5

Sujet:

Background: Complement component 5 is a protein that in humans is encoded by the C5 gene. This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mice with a homozygous mutation in this gene exhibit impaired bone fracture healing and an enhanced inflammatory response in an allergic lung disease model.

Gene Full Name: hemolytic complement

ID gène: 15139

UniProt: P06684

Pathways: Système du Complément, Carbohydrate Homeostasis