C5 anticorps (AA 19-294)

N° du produit ABIN7981403

Cet anticorps anti-C5 Polyclonal Lapin (ABIN7981403) détecte spécifiquement C5 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour C5 anticorps (AA 19-294) (ABIN7981403)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-C5 anticorps

Épitope: AA 19-294

Fonction: Anti-C5 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-C5 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse C5 recombinant protein (Position: Q19-D294).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: C5

Sujet:

Background: Complement component 5 is a protein that in humans is encoded by the C5 gene. This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mice with a homozygous mutation in this gene exhibit impaired bone fracture healing and an enhanced inflammatory response in an allergic lung disease model.

Gene Full Name: hemolytic complement

Poids moléculaire: 75 kDa

ID gène: 15139

UniProt: P06684

Pathways: Système du Complément, Carbohydrate Homeostasis