CDK9 anticorps (AA 141-372) (Fluoro594)

N° du produit ABIN7982466

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK9 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour CDK9 anticorps (AA 141-372) (Fluoro594) (ABIN7982466)

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK9 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-CDK9 anticorps (Fluoro594)

Épitope: AA 141-372

Fonction: Anti-Cdk9 Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse,rat Cdk9.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CDK9

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Autre désignation: CDK9

Sujet:

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-ed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Gene Full Name: cyclin dependent kinase 9

Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

ID gène: 1025

UniProt: P50750

Pathways: Cycle Cellulaire