CBS anticorps (AA 102-342) (Cy3)

N° du produit ABIN7982639

Cet anticorps anti-CBS Monoclonal Souris conjugué à Cy3 (Clone 7C3B7) (ABIN7982639) détecte spécifiquement CBS dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CBS anticorps (AA 102-342) (Cy3) (ABIN7982639)

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBS est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Clone: 7C3B7

Détail du produit anti-CBS anticorps (Cy3)

Épitope: AA 102-342

Fonction: Anti-CBS Antibody (monoclonal, 7C3B7) Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CBS recombinant protein (Position: K102-E342).

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: CBS

Sujet:

Background: CBS, Cystathionine Beta-Synthase, catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity. The CBS gene, which is mapped to chromosome 21q22, contains 23 exons, ranging in size from 42 to 299 bp. The human CBS protein can substitute for the endogenous yeast CBS protein in Saccharomyces cerevisiae. The catalytic domain of the CBS protein is located in the N-terminal 409 amino acids, and a regulatory domain is located in the C-terminal 142 amino acids.A mutation that deletes the C-terminal 145 amino acids of CBS could restore activity of several CBS mutant alleles found in homocystinurics.

Gene Full Name: cystathionine beta-synthase like

ID gène: 875

UniProt: P35520