DOCK2 anticorps (AA 560-1809) (Fluoro488)

N° du produit ABIN7984584

Cet anticorps Lapin Polyclonal détecte spécifiquement DOCK2 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DOCK2 anticorps (AA 560-1809) (Fluoro488) (ABIN7984584)

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK2 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-DOCK2 anticorps (Fluoro488)

Épitope: AA 560-1809

Fonction: Anti-DOCK2 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DOCK2 recombinant protein (Position: E560-T1809).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DOCK2

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Autre désignation: DOCK2

Sujet:

Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. Mutations in this gene result in immunodeficiency 40 (IMD40), a combined form of immunodeficiency that affects T cell number and function, also with variable defects in B cell and NK cell function.

Gene Full Name: dedicator of cytokinesis 2

ID gène: 1794

UniProt: Q92608