RAD51C anticorps (Middle Region) (Fluoro488)

N° du produit ABIN7985986

L’anticorps anti-RAD51C Polyclonal Lapin est utilisé pour la détection de RAD51C dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour RAD51C anticorps (Middle Region) (Fluoro488) (ABIN7985986)

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-RAD51C anticorps (Fluoro488)

Épitope: Middle Region

Fonction: Anti-Rad51C Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by eight amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Rad51C, different from the related mouse sequence by eight amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C

Sujet:

Background: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Gene Full Name: RAD51 paralog C

ID gène: 5889

UniProt: O43502

Pathways: Réparation de l'ADN