RAD51C anticorps (AA 11-342) (HRP)

N° du produit ABIN7986001

L’anticorps anti-RAD51C Polyclonal Lapin est utilisé pour la détection de RAD51C dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour RAD51C anticorps (AA 11-342) (HRP) (ABIN7986001)

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAD51C anticorps (HRP)

Épitope: AA 11-342

Fonction: Anti-RAD51C Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RAD51C recombinant protein (Position: Q11-K342).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C

Sujet:

Background: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Gene Full Name: RAD51 paralog C

ID gène: 5889

UniProt: O43502

Pathways: Réparation de l'ADN