DRD5 anticorps (AA 1-477) (Cy3)

N° du produit ABIN7986263

Cet anticorps anti-DRD5 Polyclonal Lapin conjugué à Cy3 (ABIN7986263) détecte spécifiquement DRD5 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DRD5 anticorps (AA 1-477) (Cy3) (ABIN7986263)

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD5 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-DRD5 anticorps (Cy3)

Épitope: AA 1-477

Fonction: Anti-DRD5 Antibody Cy3 Conjugated

Homologie: Human DRD5 shares 82.3%,82.4% amino acid (aa) sequence identity with mouse,rat DRD5,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DRD5 recombinant protein (Position: M1-H477). Human DRD5 shares 82.3% and 82.4% amino acid (aa) sequence identity with mouse and rat DRD5, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DRD5

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Autre désignation: DRD5

Sujet:

Background: D(1B) dopamine receptor(DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

Gene Full Name: dopamine receptor D5

ID gène: 1816

UniProt: P21918

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity