PVRL2 anticorps (PE-Cy7)

N° du produit ABIN749031

Cet anticorps anti-PVRL2 est un anticorps Lapin Polyclonal détectant PVRL2 dans WB et FACS. Adapté pour Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour PVRL2 anticorps (PE-Cy7) (ABIN749031)

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PVRL2 est conjugé à/à la PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-PVRL2 anticorps (PE-Cy7)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human nectin 2

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PVRL2

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Autre désignation: CD112

Sujet:

Synonyms: HVEB, PRR2, CD112, PVRR2, Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, Poliovirus receptor-related protein 2, PVRL2

Background: Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.

Poids moléculaire: 58kDa

ID gène: 5819

UniProt: Q92692

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization