ERN2 anticorps (AA 517-919) (PE)

N° du produit ABIN7987661

Cet anticorps anti-ERN2 Polyclonal Lapin conjugué à PE (ABIN7987661) détecte spécifiquement ERN2 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ERN2 anticorps (AA 517-919) (PE) (ABIN7987661)

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERN2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-ERN2 anticorps (PE)

Épitope: AA 517-919

Fonction: Anti-ERN2 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ERN2 recombinant protein (Position: K517-P919).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ERN2

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Autre désignation: ERN2

Sujet:

Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

Gene Full Name: endoplasmic reticulum to nucleus signaling 2

ID gène: 10595

UniProt: Q76MJ5