ERN2 anticorps (AA 517-919)

N° du produit ABIN7987663

L’anticorps anti-ERN2 Polyclonal Lapin est utilisé pour la détection de ERN2 dans des échantillons de Humain. Il a été validé pour ELISA, WB et FACS.

Aperçu rapide pour ERN2 anticorps (AA 517-919) (ABIN7987663)

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERN2 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-ERN2 anticorps

Épitope: AA 517-919

Fonction: Anti-ERN2 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-ERN2 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ERN2 recombinant protein (Position: K517-P919).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ERN2

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Autre désignation: ERN2

Sujet:

Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

Gene Full Name: endoplasmic reticulum to nucleus signaling 2

Poids moléculaire: 102 kDa

ID gène: 10595

UniProt: Q76MJ5