EIF4E anticorps (AA 18-217)
Aperçu rapide pour EIF4E anticorps (AA 18-217) (ABIN7989044)
Antigène
Voir toutes EIF4E AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 18-217
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Fonction
- Anti-EIF4E Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-EIF4E Antibody. Tested in WB, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human EIF4E recombinant protein (Position: E18-V217).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Autre désignation
- EIF4E
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Sujet
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Background: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Gene Full Name: eukaryotic translation initiation factor 4E
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Poids moléculaire
- 25 kDa
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ID gène
- 1977
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UniProt
- P06730
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Pathways
- BCR Signaling
Antigène
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