Filamin A anticorps (AA 451-638) (Fluoro550)

N° du produit ABIN7990878

Cet anticorps Souris Monoclonal détecte spécifiquement Filamin A dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Filamin A anticorps (AA 451-638) (Fluoro550) (ABIN7990878)

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filamin A est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Clone: 3F8

Détail du produit anti-Filamin A anticorps (Fluoro550)

Épitope: AA 451-638

Fonction: Anti-Filamin A/FLNA Antibody (monoclonal, 3F8) Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Filamin A/FLNA recombinant protein (Position: E451-Q638).

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: FLNA

Sujet:

Background: Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: filamin A

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location