FKBP15 anticorps (AA 19-1210) (Fluoro488)

N° du produit ABIN7990954

L’anticorps anti-FKBP15 Polyclonal Lapin est utilisé pour la détection de FKBP15 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour FKBP15 anticorps (AA 19-1210) (Fluoro488) (ABIN7990954)

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP15 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-FKBP15 anticorps (Fluoro488)

Épitope: AA 19-1210

Fonction: Anti-FKBP135/FKBP15 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FKBP135/FKBP15 recombinant protein (Position: A19-D1210).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur FKBP15

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Autre désignation: FKBP15

Sujet:

Background: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

Gene Full Name: FKBP prolyl isomerase family member 15

ID gène: 23307

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interactome