FLT3 anticorps (AA 62-295) (APC)

N° du produit ABIN7991190

Cet anticorps Lapin Polyclonal détecte spécifiquement FLT3 dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour FLT3 anticorps (AA 62-295) (APC) (ABIN7991190)

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-FLT3 anticorps (APC)

Épitope: AA 62-295

Fonction: Anti-Flt3/CD135 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse Flt3 / CD135 recombinant protein (Position: E62-E295).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur FLT3

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Autre désignation: Flt3

Sujet:

Background: Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.

Gene Full Name: FMS-like tyrosine kinase 3

ID gène: 14255

UniProt: Q00342

Pathways: Signalisation RTK