GFRA2 anticorps (AA 30-425) (Fluoro550)

N° du produit ABIN7993029

Cet anticorps Lapin Polyclonal détecte spécifiquement GFRA2 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GFRA2 anticorps (AA 30-425) (Fluoro550) (ABIN7993029)

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA2 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-GFRA2 anticorps (Fluoro550)

Épitope: AA 30-425

Fonction: Anti-GFRA2 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GFRA2

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Autre désignation: GFRA2

Sujet:

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: GDNF family receptor alpha 2

ID gène: 2675

UniProt: O00451