GAB2 anticorps (AA 162-504) (HRP)

N° du produit ABIN7995136

L’anticorps anti-GAB2 Polyclonal Lapin est utilisé pour la détection de GAB2 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour GAB2 anticorps (AA 162-504) (HRP) (ABIN7995136)

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAB2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GAB2 anticorps (HRP)

Épitope: AA 162-504

Fonction: Anti-GAB2 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GAB2 recombinant protein (Position: S162-R504).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GAB2

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Autre désignation: GAB2

Sujet:

Background: GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene

Gene Full Name: GRB2 associated binding protein 2

ID gène: 9846

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, L'effet Warburg