GADD45B anticorps (N-Term) (FITC)

N° du produit ABIN7995190

L’anticorps anti-GADD45B Polyclonal Lapin est utilisé pour la détection de GADD45B dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour GADD45B anticorps (N-Term) (FITC) (ABIN7995190)

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45B est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-GADD45B anticorps (FITC)

Épitope: N-Term

Fonction: Anti-GADD45B Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human GADD45B, which shares 94.7% amino acid (aa) sequence identity with mouse GADD45B.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GADD45B

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Autre désignation: GADD45B

Sujet:

Background: Growth arrest and DNA-damage-inducible, beta, also known as GADD45B, is a protein which in humans is encoded by the GADD45B gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

Gene Full Name: growth arrest and DNA damage inducible beta

ID gène: 4616

UniProt: O75293

Pathways: Cycle Cellulaire