GDF15 anticorps (AA 189-302) (HRP)

N° du produit ABIN7995323

Cet anticorps anti-GDF15 Polyclonal Lapin conjugué à HRP (ABIN7995323) détecte spécifiquement GDF15 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour GDF15 anticorps (AA 189-302) (HRP) (ABIN7995323)

Antigène: GDF15 (Growth Differentiation Factor 15 (GDF15))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF15 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GDF15 anticorps (HRP)

Épitope: AA 189-302

Fonction: Anti-Gdf15 Antibody HRP Conjugated

Homologie: Mouse Gdf15 shares 69.1%,96.5% amino acid (aa) sequence identity with human,rat Gdf15,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Gdf15 recombinant protein (Position: S189-A302). Mouse Gdf15 shares 69.1% and 96.5% amino acid (aa) sequence identity with human and rat Gdf15, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GDF15

Antigène: GDF15 (Growth Differentiation Factor 15 (GDF15))

Autre désignation: Gdf15

Sujet:

Background: Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. Mice lacking a functional copy of this gene exhibit progressive loss of motor neurons, and more rapid blood clot formation.

Gene Full Name: growth differentiation factor 15

ID gène: 23886

UniProt: Q9Z0J7

Pathways: SARS-CoV-2 Protein Interactome