Growth Hormone Receptor anticorps (AA 25-650) (Fluoro647)

N° du produit ABIN7995513

Cet anticorps Lapin Polyclonal détecte spécifiquement Growth Hormone Receptor dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Growth Hormone Receptor anticorps (AA 25-650) (Fluoro647) (ABIN7995513)

Antigène: Growth Hormone Receptor (GHR)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone Receptor est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Growth Hormone Receptor anticorps (Fluoro647)

Épitope: AA 25-650

Fonction: Anti-Growth hormone receptor/GHR Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Growth hormone receptor/GHR recombinant protein (Position: T25-Q650).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Growth Hormone Receptor

Antigène: Growth Hormone Receptor (GHR)

Autre désignation: Ghr

Sujet:

Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 15 A1, 15 1.84 cM. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Full Name: growth hormone receptor

ID gène: 14600

UniProt: P16882

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Response to Growth Hormone Stimulus