H2AFY anticorps (AA 180-301) (APC)

N° du produit ABIN7995940

L’anticorps anti-H2AFY Polyclonal Lapin est utilisé pour la détection de H2AFY dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour H2AFY anticorps (AA 180-301) (APC) (ABIN7995940)

Antigène: H2AFY (H2A Histone Family, Member Y (H2AFY))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFY est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-H2AFY anticorps (APC)

Épitope: AA 180-301

Fonction: Anti-H2AFY/MACROH2A1 Antibody APC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse,rat MACROH2A1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human H2AFY/MACROH2A1 recombinant protein (Position: A180-K301). Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse and rat MACROH2A1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur H2AFY

Antigène: H2AFY (H2A Histone Family, Member Y (H2AFY))

Autre désignation: MACROH2A1

Sujet:

Background: Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: macroH2A.1 histone

ID gène: 9555

UniProt: O75367