HCK anticorps (AA 14-501) (Biotin)

N° du produit ABIN7996957

L’anticorps anti-HCK Polyclonal Lapin est utilisé pour la détection de HCK dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour HCK anticorps (AA 14-501) (Biotin) (ABIN7996957)

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCK est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-HCK anticorps (Biotin)

Épitope: AA 14-501

Fonction: Anti-HCK Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HCK shares 89.2%,88.7% amino acid (aa) sequence identity with mouse,rat HCK,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HCK recombinant protein (Position: R14-R501). Human HCK shares 89.2% and 88.7% amino acid (aa) sequence identity with mouse and rat HCK, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: HCK

Sujet:

Background: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Gene Full Name: HCK proto-oncogene, Src family tyrosine kinase

ID gène: 3055

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling