ChT anticorps (AA 446-580) (Fluoro594)

N° du produit ABIN7997523

Cet anticorps Lapin Polyclonal détecte spécifiquement ChT dans FACS. Il présente une réactivité avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour ChT anticorps (AA 446-580) (Fluoro594) (ABIN7997523)

Antigène: ChT (High Affinity Choline Transporter (ChT))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ChT est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-ChT anticorps (Fluoro594)

Épitope: AA 446-580

Fonction: Anti-SLC5A7 Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SLC5A7 recombinant protein (Position: R446-Q580).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ChT

Antigène: ChT (High Affinity Choline Transporter (ChT))

Autre désignation: SLC5A7

Sujet:

Background: The high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.

Gene Full Name: solute carrier family 5 member 7

ID gène: 60482

UniProt: Q9GZV3