HTRA3 anticorps (C-Term) (Fluoro647)

N° du produit ABIN7998409

L’anticorps anti-HTRA3 Polyclonal Lapin est utilisé pour la détection de HTRA3 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour HTRA3 anticorps (C-Term) (Fluoro647) (ABIN7998409)

Antigène: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA3 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-HTRA3 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-HtrA3 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by four amino acids,and from the related rat sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HtrA3, different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HTRA3

Antigène: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Autre désignation: HTRA3

Sujet:

Background: Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.

Gene Full Name: HtrA serine peptidase 3

ID gène: 94031

UniProt: P83110