HIF3A anticorps (C-Term) (FITC)

N° du produit ABIN7999021

L’anticorps anti-HIF3A Polyclonal Lapin est utilisé pour la détection de HIF3A dans des échantillons de Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour HIF3A anticorps (C-Term) (FITC) (ABIN7999021)

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIF3A est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-HIF3A anticorps (FITC)

Épitope: C-Term

Fonction: Anti-HIF3/HIF3A Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3, different from the related rat and mouse sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HIF3A

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Autre désignation: HIF3A

Sujet:

Background: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

Gene Full Name: hypoxia inducible factor 3 subunit alpha

Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

ID gène: 64344

UniProt: Q9Y2N7

Pathways: L'effet Warburg