HIF3A anticorps (C-Term)

N° du produit ABIN7999026

Cet anticorps Lapin Polyclonal détecte spécifiquement HIF3A dans WB. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour HIF3A anticorps (C-Term) (ABIN7999026)

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIF3A est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-HIF3A anticorps

Épitope: C-Term

Fonction: Anti-HIF3/HIF3A Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by five amino acids.

Attributs du produit: Anti-HIF3/HIF3A Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3, different from the related rat and mouse sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Rat, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HIF3A

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Autre désignation: HIF3A

Sujet:

Background: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

Gene Full Name: hypoxia inducible factor 3 subunit alpha

Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

Poids moléculaire: 49 kDa

ID gène: 64344

UniProt: Q9Y2N7

Pathways: L'effet Warburg