ITGA4 anticorps (AA 41-963) (APC)

N° du produit ABIN8000337

L’anticorps anti-ITGA4 Polyclonal Lapin est utilisé pour la détection de ITGA4 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour ITGA4 anticorps (AA 41-963) (APC) (ABIN8000337)

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA4 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-ITGA4 anticorps (APC)

Épitope: AA 41-963

Fonction: Anti-Integrin Alpha 4/Itga4 Antibody APC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Integrin Alpha 4/Itga4 recombinant protein (Position: Y41-D963). Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: Itga4

Sujet:

Background: CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: integrin alpha 4

ID gène: 16401

UniProt: Q00651

Pathways: Integrin Complex