IRAK1 anticorps (AA 377-479) (PE)

N° du produit ABIN8002912

Cet anticorps anti-IRAK1 Polyclonal Lapin conjugué à PE (ABIN8002912) détecte spécifiquement IRAK1 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IRAK1 anticorps (AA 377-479) (PE) (ABIN8002912)

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-IRAK1 anticorps (PE)

Épitope: AA 377-479

Fonction: Anti-IRAK/IRAK1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IRAK recombinant protein (Position: M377-D479).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IRAK1

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Autre désignation: IRAK1

Sujet:

Background: Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

Gene Full Name: interleukin 1 receptor associated kinase 1

ID gène: 3654

UniProt: P51617

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades