IFT74 anticorps (AA 1-375) (Cy3)

N° du produit ABIN8003136

L’anticorps anti-IFT74 Polyclonal Lapin est utilisé pour la détection de IFT74 dans des échantillons de Humain, Rat, Souris et Singe. Il a été validé pour FACS.

Aperçu rapide pour IFT74 anticorps (AA 1-375) (Cy3) (ABIN8003136)

Antigène: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFT74 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-IFT74 anticorps (Cy3)

Épitope: AA 1-375

Fonction: Anti-IFT74 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IFT74

Antigène: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Autre désignation: IFT74

Sujet:

Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

Gene Full Name: intraflagellar transport 74

ID gène: 80173

UniProt: Q96LB3

Pathways: Signalisation Hedgehog, Chromatin Binding