IFT74 anticorps (AA 1-375)

N° du produit ABIN8003145

L’anticorps anti-IFT74 Polyclonal Lapin est utilisé pour la détection de IFT74 dans des échantillons de Humain, Rat, Souris et Singe. Il a été validé pour ELISA, WB, IHC et FACS.

Aperçu rapide pour IFT74 anticorps (AA 1-375) (ABIN8003145)

Antigène: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFT74 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-IFT74 anticorps

Épitope: AA 1-375

Fonction: Anti-IFT74 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Attributs du produit: Anti-IFT74 Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IFT74

Antigène: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Autre désignation: IFT74

Sujet:

Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

Gene Full Name: intraflagellar transport 74

Poids moléculaire: 69 kDa

ID gène: 80173

UniProt: Q96LB3

Pathways: Signalisation Hedgehog, Chromatin Binding