ISL1 anticorps (AA 118-161) (PE)

N° du produit ABIN8003330

Cet anticorps Lapin Polyclonal détecte spécifiquement ISL1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ISL1 anticorps (AA 118-161) (PE) (ABIN8003330)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-ISL1 anticorps (PE)

Épitope: AA 118-161

Fonction: Anti-Islet 1/ISL1 Antibody PE Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ISL1 shares 100% amino acid (aa) sequence identity with both mouse,rat ISL1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Islet 1/ISL1 recombinant protein (Position: D118-E161). Human ISL1 shares 100% amino acid (aa) sequence identity with both mouse and rat ISL1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1

Sujet:

Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Gene Full Name: ISL LIM homeobox 1

ID gène: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding