IDH3A anticorps (AA 69-425) (Biotin)

N° du produit ABIN8003443

Cet anticorps anti-IDH3A Polyclonal Lapin conjugué à Biotin (ABIN8003443) détecte spécifiquement IDH3A dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour IDH3A anticorps (AA 69-425) (Biotin) (ABIN8003443)

Antigène: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3A est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IDH3A anticorps (Biotin)

Épitope: AA 69-425

Fonction: Anti-IDH3A Antibody Biotin Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PAICS shares 95.2%,96.1% amino acid (aa) sequence identity with mouse,rat PAICS,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAICS recombinant protein (Position: Q69-L425). Human PAICS shares 95.2% and 96.1% amino acid (aa) sequence identity with mouse and rat PAICS, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IDH3A

Antigène: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Autre désignation: IDH3A

Sujet:

Background: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

ID gène: 3419

UniProt: P50213