JUP anticorps (AA 556-745) (HRP)

N° du produit ABIN8003724

L’anticorps anti-JUP Polyclonal Lapin est utilisé pour la détection de JUP dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour JUP anticorps (AA 556-745) (HRP) (ABIN8003724)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-JUP anticorps (HRP)

Épitope: AA 556-745

Fonction: Anti-gamma Catenin/JUP Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse,rat gamma Catenin.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet:

Background: Junction plakoglobin (JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to β-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Gene Full Name: junction plakoglobin

Sequence Similarities: Belongs to the beta-catenin family.

ID gène: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location